Posted May 22nd, 2012 by Konrad Förstner
It’s time to resurrect this blog after a long time of silence. So let’s start with a quicky. I hope to manage to write more frequently again.
Today Jean-Marc Ghigo – principal investigator at the Institute Pasteur – gave at talk at our instiute. He presented his research results which reveal that volatile molecules can mediate long-range chemical interactions between physically separated bacteria. For example ammonia was shown to lead to antibiotic resistant phenotype in E. coli . Such an influence was found for many other volatile agents. I think is is quite important to keep the effect of such chemicals interference in mind when doing wed-lab work (luckily I don’t do that). Just think about the situation that just before you start your experiment you clean the desk with a detergent that contains ammonia. This sounds like a nightmare for reproducibility of biological experiments to me.
 Bernier SP, Létoffé S, Delepierre M, Ghigo JM. Biogenic ammonia modifies antibiotic resistance at a distance in physically separated bacteria. Mol Microbiol. 2011 Aug;81(3):705-16. doi:10.1111/j.1365-2958.2011.07724.x. Epub 2011 Jun 23. PMID: 21651627
Posted August 5th, 2010 by Konrad Förstner
It looks like Michael Kuhn kick-started the Flattr wave for the science blogging scene. As not everybody knows what this service is – here is a short intro: Flattr is a social micropayment system that makes it very easy to pay content creators like bloggers, podcasters, programmers or photographs little amounts of money just with a click (okay, after a previous registration and money transfer). Your donation (e.g. 5 Euro) is equally shared between all the items you flattred in a month. Especially in Germany Flattr took off in the blogging and podcasting scene – one of the reasons might be Peter Sunde‘s talk at the re:publica 2010 in Berlin. Until now the projects is in a invitation-based closed beta stage. Recently Tim Pritlove – one of the most important podcasters in Germany – roughly measured that there are currently around 26.000+ Flattr users.
What’s about Flattr and science / scientific communication? Until Michael’s tweet I didn’t consider it as an option and embedded Flattr buttons only in my coding related blog. Somehow I had a weird feeling putting them on this science related blog (although this is not the only topic of it). Maybe this was due to my personal understanding that science is not about money. Maybe it was due to the fact that scientist have usually (or do I need to say ideally?) a fixed income and don’t need extra money. What ever it was I guess we should give it also in this field a try. As for the generation of other content Flattr could give new impulses and opportunists for scientific activities and communication. The currency of science is usually attribution not necessarily money. Flattr is a mixture of both. People pay attribution to your work but also are willing to give you a little piece of their resources.
The main application of Flattr in the scholarly field might be to motivate more scientist to communicate their research to the public. And this hopefully without locking content away but making the knowledge a common good by using open licenses. It might be a long way but maybe this service could enable some scientist to become semi-professional communicators of science. I am not sure if it will be a driving force for the communication of scientists to scientists. I also doubt that it can be used to fund (semi)-professional research in the near future. We will see – let’s give it a chance.
Photo by David Goehring.
Posted June 14th, 2010 by Konrad Förstner
It has been quite a while since I was working in a wet lab the last time but I still have a lot of respect for the busy bees generating data there. It’s hard to imagine such a lab without personal computers which get data automatically from the detecting apparatus or manually from the experimenter. But as far as I am informed the stream of information of an experiment is mostly going in one direction – from the experimenter to the computer. Using the channel from the data pool to the experimenter could offer interesting opportunities to improve research. There are devices like electronic lab journals but I think about a further step: Augmented reality (AR) for the wet lab.
I prepared two quick and dirty mock-ups (upper part = raw image, lower part = image + data layer) and hope they are sufficient to give a rough impression of the idea. In both cases QR codes would be used to identify the object. A smartphone with a camera would detect these items (e.g. microtrubes or petri dishes) and overlay the given image with information about the experiment. In the case of the petri dish the size of the colony could be measured (assuming that the petri dish can be used as a reference) additionally and stored as part of the experiment. The applications of such systems are endless and all the technologies are available for low cost. It’s just about connecting everything. Is any project bringing this to reality already? It’s somehow hard to believe that this is not the case but I couldn’t find anything like it. This could be a cool community project.
PS: I have to admit there are some small technical hurdles in my examples. The QR codes are pretty small and my smartphone was unable to interpret the code correct if they are bend around something.
Attribution: Original images “32-day-wristband-culture” by Flickr user justinbaeder and Bacteria solution by Flickr user kaibara.
Posted June 1st, 2010 by Konrad Förstner
Some weeks ago my brother who works in the field of Neuroscience made me aware of a genealogical tree of his scientific community called NeuroTree. This inspired me to think about such a tree for science in general which might give interesting insights into the scientific community and reveal connections that usually only insiders have (or would like to have). Michael Kuhn pointed out that such an endeavor exists already. In fact the NeuroTree is a part of this general Academic Family Tree. Until recently it comprised 15 subtrees of different scientific communities. As a tree for Computational Biology/Bioinformatics was missing at that point I asked Stephen V David who is responsible for this project if it would be possible for him to set up a tree for the Computational Biology and Bioinformatics crowd. Additionally I proposed to use a Creative Commons license (we discussed different options – Stephen decided to take the CC-BY) for its data. Soon after that the freshly planted Computational Biology Tree (suggested abbreviation: CompBioTree) got its first branches and leaves. Michael happily joined me gardening. We both hope that we are not the only ones who want to see the tree grow so please feel free to contribute.
Additionally we are open for suggestions and feedback. I have also some points in mind to improve the tree and the underlying system. To mention some:
- A new logo (the one I took is just a initial solution)
- RSS for changes
- SSL login
- Show image source
- Pubmed links
- Show history of an entry
- ORCID (if this ever comes true it would have many implication to this project e.g. they could be used a base id)
- (RESTful) API
- SVG generation
- Frequent data dumps in different formats
- Publish the software under a open source license
All of these points are nothing more than my wishes and have to be discussed with Stephen. I cannot promise anything at this point only that any feedback is welcome. Apropos feedback and communication: I first thought about creating a blog and a mailing list for updates about the tree but Micheal convinced me that this is not necessary currently. So far I created a Friendfeed group. If there is the need at some point maybe OpenWetWare could be a place to set up a blog and page for collecting ideas.
Image by Jim Linwood
Posted April 13th, 2010 by Konrad Förstner
The days of social data silos are finally counted … yesterday OneSocialWeb made a plug-in for OpenFire and a console client available for download. These two programs are the first bricks for building a distributed social network.
A screen shot of the web client
A web client and a client for Android will follow soon (I had luck – Laurent Eschenauer provide me with an account for an installation of the rudimentary web client). If you play around with the programs you will recognize that they have many rough edges and miss many functions so far – they are in a very early stage. Despite this OneSocialWeb is in my opinion on of the most promising projects in this field and a look at the protocol specification made me quite exited. Everything is build on XMPP (=> real-time) and other open standards. On the list of functions are Activity Stream over XMPP (which works currently), VCard4 over XMPP, Social Relationships and a Personal Eventing Protocol (PEP) Inbox. If you like to play around with early stage (console) tools have a look at the github repositories of the project and help to improve them.
Update: If you need an account for a running server – ping Laurent.
Posted February 9th, 2010 by Konrad Förstner
Last week I registered to Cliqset in the hope to finally find the last über-aggretator I need to combine all my live stream services. As my expectations were not fulfilled I tried to explore my disappointment and to find out what I was missing in all the aggregators I tested so far. In my opinion the problem is that platforms like friendfeed, cliqset, lifestream.ff etc. are build to spread my content to other platforms and to bundle my various output streams into one. The function that is missing is the insertion of streams of other people than me from outside the platform. An example might make this clearer: I would like to read the postings of all the people I follow in e.g. twitter, identi.ca and friendfeed in one service. This service could be friendfeed. What I see there in my personal view are all the streams of people who have a friendfeed account and who I follow. If all these people would have a twitter account and added that one to their friendfeed stream I could theoretically unfollow them on twitter and just read their posts on friendfeed. Unfortunately this is not reality and only a fraction of the people who I follow on twitter and identi.ca own a friendfeed account. So I would like to tell friendfeed to take all the status messages of the people I follow on twitter and identi.ca and integrate them like postings of friendfeed users into the stream that I see. At this point redundant postings (same person – same text – different platforms) could be removed.
Let’s talk tech for the case that I still could not make myself understood: I want a combined, real-time, non-redundant stream of
If you step back now and have a look at what I just have described you see that this is kind of a real-time RSS reader (time for PubSub, isn’t it?) including all the other goodies that friendfeed offers (e.g. sending to multiple platforms, commenting). An other description would be a multi-service client for status services.
My question: I this already possible to do so with friendfeed or one of it’s clones and I just missed it? Or am I the only one interested in that? Is there something around like this? Even Regine who is usually quite informed about the options of such tools could not help me (but inspired me to do a little visualization). … Maybe the solution will be Google buzz that just arrived (not yet available for me).
Update: Google buzz seems to be more a part of the problem than a part of the solutions. Maybe Cliqset was not a too bad hint. It offers a FeedProxy for many other services and makes it very easy to harvest the streams nicely wrapped using Activity Streams. This could be easily used to write something from scratch. But I still hope to find a ready solution.
Posted February 2nd, 2010 by Konrad Förstner
It’s good to see that there is a growing movement that aims to free the online identity and the social graph from silo platforms with dubious privacy agreements and to offer decentralized entities as new harbors. While I like the idea of the Diso Project that tries to implement decentralized social networks by extending server-located platforms like WordPress (and luckily being heavily based on open standards) there is another approach to tackle the problem – by putting the identity in your browser. Aza Raskin stated that identity will be one of the defining themes of the web in the next five years and made hopes that Firefox will offer such functionality in the future. Unfortunately it looks like the Firefox community has only some mocks to offer currently. Interestingly there has been some research going on in this field in the last years that might point to solutions for some of the problems which have to be overcome: There are social networks that are based on the P2P concept (more precisely F2F) and offer a high level of privacy granularity by working with a so called Matryoshkas concept. One of the main problems is the persistence of a user’s personal data in the case that he is offline. There is a good introductionary paper discussing (and solving) these issues and proposing an implementation called Safebook . Other early stage projects are Lifesocial and Persona. While I think the basic idea of P2P-based distributed social networks is the right direction I think it is done wrongly by not integrating it into the browser which is the natural habitat for the online identity. This might be partly due to technical limitations of browser plugins.
Another issue is the following: As far as I understand the profile data would be displayed in the browser for users that use this networking functionality. But in many cases it would be needed to present parts of the identity to the public e.g. on a plain web page. So based on the privacy setting the underlying identity data would have to be rendered to HTML and send to a server. Sounds technically trivial but might have further privacy implications.
For me there is also the burning question of how the concepts could be applied to replace specialized networks with many different purposes and requirements (like Couchsurfing) to get “one to rule them all”.
Currently it is not clear that decentralized networks will win against their centralized counterparts in the near future. The raising awareness of privacy and of the value of online identities might be driving forces to make that shift happen. I expect that we will observe quite some development in this area soon.
 Cutillo, Leucio Antonio;Molva, Refik;Strufe, Thorsten,
Leveraging social links for trust and privacy in networks, INetSec 2009. Open Research Problems in Network Security. April 23-24, 2009. Zurich, Switzerland
Photo by fadderuri.
Posted November 14th, 2009 by Konrad Förstner
Finally I finished a new theme for my page that suits my functional and aesthetic wishes. Currently I think it is too early for HTML5/CSS3 but I will move to it at some point based on the current theme. Additionally I changed the name of the blog to something more meaningful – “dao of flow”. After all this I hope to find time to have a look at all the blog post ideas that are sitting in my todo list and are begging to be written down.